It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
A: The idea of boldenone propionate is great, as personal opinion. Boldenone has a relatively favorable side effect profile compared to most other anabolic steroids . Conversion to estrogen is low, and if anything the modest amount of conversion can be beneficial if no other aromatizing steroid is being used. Unlike testosterone , it’s not potentiated in the skin or scalp. Boldenone typically has little in the way of adverse effect on mood. The most common problems are increased appetite (in cases where that’s experienced as a problem) and at higher doses, sometimes a feverish feeling. But in general, it’s very well tolerated at modest dosages such as up to 400-500 mg/week and sometimes more.