¶ Dose reduction and/or serum Theophylline concentration measurement is indicated whenever adverse effects are present, physiologic abnormalities that can reduce Theophylline clearance occur (., sustained fever), or a drug that interacts with Theophylline is added or discontinued (see WARNINGS ).
Once-Daily Dosing: The slow absorption rate of this preparation may allow once-daily administration in adult non-smokers with appropriate total body clearance and other patients with low dosage requirements. Once-daily dosing should be considered only after the patient has been gradually and satisfactorily titrated to therapeutic levels with q12h dosing. Once-daily dosing should be based on twice the q12h dose and should be initiated at the end of the last q12h dosing interval. The trough concentration (C min ) obtained following conversion to once-daily dosing may be lower (especially in high clearance patients) and the peak concentration (C max ) may be higher (especially in low clearance patients) than that obtained with q12h dosing. If symptoms recur, or signs of toxicity appear during the once-daily dosing interval, dosing on the q12h basis should be reinstituted.
It is essential that serum Theophylline concentrations be monitored before and after transfer to once-daily dosing.
Food and posture, along with changes associated with circardien rhythm, may influence the rate of absorption and / or clearance rates of Theophylline from extended-release dosage forms administered at night. The exact relationship of these and other factors to nighttime serum concentrations and the clinical significance of such findings require additional study. Therefore, it is not recommended that Theophylline extended-release once-daily dosing be administered at night.
It’s no secret there exist a strong anti-steroidal population and as this “anti” feeling is often so emotionally based it can produce some laughable claims. If you’ve been around the performance enhancing game for any length of time you’re familiar with all the names and acronyms so this will probably make you laugh. Yes, there are a few street names for steroids such as juice or roids but those are some very generic terms and really don’t point to anything specific. We went to a handful of the anti-steroid websites so desperate to paint anabolic hormones in a bad light and they have made up their own street names for steroids that are quite humorous and they include “Pumpers, Gym Candy, Arnolds, Stackers, Balls and Bulls, A’s, Weight Trainers.” “Weight Trainers” are you serious, Arnolds? If that didn’t make you laugh a little then you don’t have a sense of humor but the sad truth is these websites are real and many of them are funded by your government.
KEEP OUT OF REACH OF CHILDREN. WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 21 YEARS. Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of,prostate cancer prostate enlargement, heart disease, low “good” cholesterol (HDL), or if you are using any other dietary supplement,prescription drug, or over-the-counter drug. Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heart beat, dizziness, blurred vision, or other similar symptoms. Made in a facility that may process dairy, peanuts, tree nuts, wheat, fish, barley and shellfish. Do not use if governed by any body that prohibits hormone use.