Haldol im vs po

3 to 12 years and 15 to 40 kg :
-Initial dose: mg/day orally in 2 to 3 divided doses
-Maintenance dose: to mg/kg/day

Comments :
-The daily dose may be increased every 5 to 7 days in mg increments.
-There is little evidence that behavior improvement is further enhanced by doses greater than 6 mg/day.
-Limitation of use: Treatment should be reserved for patients with severe behavior problems and/or hyperactive children only after failure to respond to psychotherapy or medications (other than antipsychotics).

Uses :
-Treatment of severe behavior problems in children, including combative, explosive hyperexcitability not accounted for by immediate provocation
-Short-term treatment of hyperactive children with excessive motor activity and accompanying conduct disorder with impulsivity, difficulty sustaining attention, aggressiveness, mood lability, and/or poor frustration tolerance.

At the request of the Pharmacovigilance Department of the Italian Drug Agency (AIFA), the sponsor (Johnson & Johnson) performed two post-marketing analyses of QT interval prolongation and TdP with haloperidol administration (oral or injectable).  In one analysis, the sponsor searched their Benefit Risk Management worldwide safety database for QT prolongation -related adverse event reports received through June 30, 2005.  This search identified 229 reports, many of which the sponsor described as confounded by concomitant QT-prolonging drugs or medical conditions.  The reports included 73 cases of TdP, eleven of which were fatal.  Eight of the eleven fatal cases involved intravenous administration of various doses of haloperidol. 

Work: Research has demonstrated that people with mental illness who have difficulty with memory, problem solving, processing speed, and attention are more likely to be unemployed or have a lower occupational status. In many ways this is not surprising. Critical thinking has been identified as one of the most important skills that people need to compete in the modern workforce. Yet critical thinking/problem solving is often impaired in people with persistent mental illness. The problems that can arise at work when someone has difficulty paying attention, concentrating and remembering are also obvious. Most jobs are not just rote and repetitive, but require people to remember new information or deal with changing demands. This is difficult when cognition is not working well.

Haldol im vs po

haldol im vs po

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haldol im vs pohaldol im vs po

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