Individuals who take testosterone injections are more likely to develop cardiovascular issues, according to a recent investigation by J. Bradley Layton, Christoph R. Meier, Julie L. Sharpless, et al. The study, however, focused on individuals who used short-acting testosterone injections. These often result in spiky testosterone levels which make such patients vulnerable to the cardiovascular risks. However, some critics believe that the study has some shortcomings. But, they had their reservations mainly because the lifestyle and personal preferences of the subjects weren’t noted in the study.
Other significant adverse effects of testosterone supplementation include acceleration of pre-existing prostate cancer growth in individuals who have undergone androgen deprivation; increased hematocrit , which can require venipuncture in order to treat; and, exacerbation of sleep apnea .  Adverse effects may also include minor side-effects such as acne and oily skin, as well as, significant hair loss and/or thinning of the hair, which may be prevented with 5-alpha reductase inhibitors ordinarily used for the treatment of benign prostatic hyperplasia , such as finasteride .  Exogenous testosterone may also cause suppression of spermatogenesis , leading to, in some cases, infertility.  It is recommended that physicians screen for prostate cancer with a digital rectal exam and prostate-specific antigen (PSA) level before starting therapy, and monitor PSA and hematocrit levels closely during therapy. 
The content on this website is intended to provide general information about our clinic and services, and should not be mistaken for medical advice. We prescribe testosterone and other hormone therapy only after an in-office, comprehensive evaluation indicates that hormone therapy is safe and medically necessary. We do not prescribe testosterone or human growth hormone (HGH) or human chorionic gonadotropin (HCG) solely for bodybuilding or athletic performance enhancement, or for solely "anti-aging" purposes. We do not prescribe HGH for off-label uses under any circumstances.
NOTE: Our physicians are "naturopathic physicians," not "physicians" or "osteopathic physicians," and neither "TRT" nor "integrative men's health" are "medical specialties."
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