Since a float is not in the flow, non-positioned block boxes created before and after the float box flow vertically as if the float did not exist. However, the current and subsequent line boxes created next to the float are shortened as necessary to make room for the margin box of the float. A line box is next to a float when there exists a vertical position that satisfies all of these four conditions: (a) at or below the top of the line box, (b) at or above the bottom of the line box, (c) below the top margin edge of the float, and (d) above the bottom margin edge of the float. Note: this means that floats with zero outer height or negative outer height do not shorten line boxes. If a shortened line box is too small to contain any content, then the line box is shifted downward (and its width recomputed) until either some content fits or there are no more floats present. Any content in the current line before a floated box is reflowed in the same line on the other side of the float. In other words, if inline-level boxes are placed on the line before a left float is encountered that fits in the remaining line box space, the left float is placed on that line, aligned with the top of the line box, and then the inline-level boxes already on the line are moved accordingly to the right of the float (the right being the other side of the left float) and vice versa for rtl and right floats.
Thus any doctor that is "watching" or "monitoring" your slightly high calcium to see if it goes any higher doesn't understand much about hyperparathyroidism. First, how high it is doesn't matter! A "slightly" high calcium for a number of years will cause tremendous troubles (discussed in great detail elsewhere). Second, this doctor is hurting you, because "keeping an eye on the calcium level" means he/she is adding to the duration of the high calcium, and it is the duration (how long it has been high) that causes all the troubles. The rate of high blood pressure, breast cancer, prostate cancer, renal failure, osteoporosis, A-fib, blood clots, hair loss, kidney stones, bone pain, muscle spasms, memory loss, and heart attack are all related to the duration of calcium (in years) over mg/dl. How high the calcium has become is a very poor indicator of the severity of primary hyperparathyroidism.
However, aging is seen as a progressive failure of homeodynamics–systemic preservation of homeostasis , involving genes for maintenance and repair, stochastic events leading to molecular damage and molecular heterogeneity, and chance events determining the probability of death. Since complex and interacting systems of maintenance and repair comprise the homeodynamic space of a biological system, aging is considered to be a progressive shrinkage of homeodynamic space mainly due to increased molecular heterogeneity. [ citation needed ] In 2013, a group of scientists defined nine hallmarks of aging that are common between organisms with emphasis on mammals: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis , deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication.